Potentials of synthesised Lessertia montana zinc oxide nanoparticles on free radicals-mediated oxidative stress and carbohydrate-hydrolysing enzymes

The study evaluated the effects of green absorbed zinc oxide nanostructures on oxidative stress-mediated free radicals and carbohydrate-hydrolysing enzymes. synthesised Lessertia montana nanoparticles were characterised using different spectroscopic, microscopic, diffraction techniques. activity L. ZnONPs against 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid (ABTS), metal chelating assay, alpha-amylase alphaglucosidase determined standard methods. stable (NPs), appeared cubical (predominantly) in shape, nanometre range sizes. NPs are very active (p < 0.05) DPPH alpha-glucosidase (0.120 0.037 g/L, respectively) when compared with other samples controls, quercetin (0.349 g/L) acarbose (0.065 g/L). However, their interaction revealed a good ABTS (0.093 scavenging an excellent (0.027 effect to samples. mode inhibition enzymes by was competitive non-competitive, respectively. outcomes that possessed potential mitigate stress diabetes vitro.